Omar Al-Qudah 

Email: omaralqudah5555@gmail.com

Location: Ajloun, Jordan

ResearchGate:  link available

CV:  Download here 

Thesis Title: Synthesis and Experimental Characterization of Cadmium-Doped Greigite Nanoparticles (Fe₃S₄@Cd) for Biomedical Applications

Thesis Description:

Omar’s research focuses on the synthesis and advanced characterization of redox-active cadmium-doped Greigite nanocomposites (Fe₃S₄@Cd) for multifunctional biomedical applications, particularly their potential in anticancer therapy, Fenton-like catalytic activity, and synergy with chemotherapeutic drugs such as doxorubicin.

The nanoparticles were synthesized using a controlled solvothermal approach and analyzed using a comprehensive suite of techniques, including XRD, SEM/TEM, UV-Vis, FTIR, XRF, and TGA. XRD confirmed the coexistence of Greigite and Pyrite phases across all samples, while the appearance of CdS peaks at higher doping levels (≥8 wt.%) verified successful Cd incorporation and phase evolution. Cd doping produced notable effects on lattice strain, crystallite size, and particle morphology, promoting the formation of flower-like aggregates and influencing overall crystallinity. Optical measurements revealed non-linear bandgap variations with increasing Cd content, supporting a strong structure–property relationship.

Chemical incorporation of Cd was further validated by FTIR and XRF, while TGA demonstrated improved thermal stability in doped nanocomposites, indicating enhanced structural robustness. Functionally, the materials exhibited concentration-dependent Fenton-like redox activity, generating low ROS levels at therapeutic concentrations and higher oxidative response at elevated doses. Biological evaluations showed excellent biocompatibility toward normal HDF cells and selective cytotoxicity against A549 lung cancer cells, particularly in undoped, 5 wt.%, and 15 wt.% Cd-doped samples. Although minimal direct toxicity was observed against MCF-7 cells, the nanoparticles catalyzed doxorubicin degradation under moderate oxidative conditions, decreasing its cytotoxicity during combined treatment.
Status:

He graduated and is currently working as a Research Assistant.